December 10, 2015 16:00 - 17:00
BSI Central Building 1F Seminar Room
Multipotent precursors are plastic cells that generate different, stable fates at the correct number, place and time, to allow tissue and organ formation. The molecular pathways driving the progression from multipotent precursors toward stable and specific identities remain poorly understood. We have found that the Drosophila glial fate determinant acts as a ‘time-bomb’ by specifically inducing its own extinction once the correct transcriptional program has been stably activated.
Our ability to respond and adapt to the internal and external environments relies on our nervous and immune systems, through the presence of glia and blood cells. In vertebrates, these two cell types have evolved from different layers and require different molecular cascades. In the simple Drosophila model, however, the same transcription factor controls the two cell populations, opening novel perspectives to understand the bases of nervous system and immune system evolution.
- Open to Public
- Adrian Moore [Adrian Moore, Genetic Control of Neuronal Architecture ]
Name: Adrian Moore