RIKEN BRAIN SCIENCE INSTITUTE (理研BSI)

Events

[Forum] Hongkui Zeng, Allen Institute for Brain Science

“ Genetic Approaches to Brain Circuit Mapping and Cell Type Characterization ”

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Date

September 21, 2017 16:00 - 17:00

Location

BSI Central Building 1F Seminar Room

Abstract

The brain circuit is an intricately interconnected network of numerous cell types. Combining genetic tools with large-scale imaging and single-cell analysis technologies presents us with the opportunity to gain systematic understanding of the properties, interconnections and function of these cell types. At the Allen Institute, we are building multiple platforms, including single-cell transcriptomics, single and multi-patching electrophysiology, 3D reconstruction of neuronal morphology, high throughput brain-wide connectivity mapping, and large-scale neuronal activity imaging, to characterize the transcriptomic, physiological, morphological, and connectional properties of different types of neurons in a standardized way, towards a taxonomy of cell types and a description of their connectivity matrix for the mouse visual cortico-thalamic system. Building such knowledge base lays the foundation towards the understanding of the computational mechanisms of cortical function.

More Detail

Language
English
Admission
Open to Public
Host
Tetsuo Yamamori [Tetsuo Yamamori, Molecular Analysis for Higher Brain Function ]
Contact
Name: Tetsuo Yamamori
Email: