RIKEN's New Research Center for Brain Science: 脳神経科学研究センター(理研CBS)ウェブサイト


Faculty Detail / 研究室詳細



Spatial learning, In vivo physiology, Circuit genetics

Thomas, McHugh J.




主な発表論文 全て表示する

  1. 1

    Roman Boehringer, Denis Polygalov, Arthur J.Y. Huang, Steven J. Middleton, Vincent Robert, Marie E. Wintzer, Rebecca A. Piskorowski, Vivien Chevaleyre, and Thomas J. McHugh: "Chronic Loss of CA2 Transmission Leads to Hippocampal Hyperexcitability", Neuron, 94(3), 642-655.e9 (2017)

  2. 2

    Middleton SJ, and McHugh TJ: "Silencing CA3 disrupts temporal coding in the CA1 ensemble.", Nat Neurosci (2016)

  3. 3

    Yu LM, Polygalov D, Wintzer ME, Chiang MC, and McHugh TJ: "CA3 Synaptic Silencing Attenuates Kainic Acid-Induced Seizures and Hippocampal Network Oscillations.", eNeuro, 3(1) (2016)

  4. 4

    Chinnakkaruppan A, Wintzer ME, McHugh TJ, and Rosenblum K: "Differential Contribution of Hippocampal Subfields to Components of Associative Taste Learning.", J Neurosci, 34(33), 11007-11015 (2014)

  5. 5

    Wintzer ME, Boehringer R, Polygalov D, and McHugh TJ: "The Hippocampal CA2 Ensemble Is Sensitive to Contextual Change.", J Neurosci, 34(8), 3056-3066 (2014)

  6. 6

    Nakashiba T, Cushman JD, Pelkey KA, Renaudineau S, Buhl DL, McHugh TJ, Barrera VR, Chittajallu R, Iwamoto KS, McBain CJ, Fanselow MS, and Tonegawa S: "Young Dentate Granule Cells Mediate Pattern Separation, whereas Old Granule Cells Facilitate Pattern Completion.", Cell (2012)

  7. 7

    Jones MW, and McHugh TJ: "Updating hippocampal representations: CA2 joins the circuit.", Trends Neurosci, 34(10), 526-35 (2011)

  8. 8

    Nakashiba T, Buhl DL, McHugh TJ, and Tonegawa S: "Hippocampal CA3 output is crucial for ripple-associated reactivation and consolidation of memory.", Neuron, 62(6), 781-7 (2009)

  9. 9

    Nakashiba T, Young JZ, McHugh TJ, Buhl DL, and Tonegawa S: "Transgenic inhibition of synaptic transmission reveals role of CA3 output in hippocampal learning.", Science, 319(5867), 1260-4 (2008)

  10. 10

    Tonegawa S, and McHugh TJ: "The ins and outs of hippocampal circuits.", Neuron, 57(2), 175-7 (2008)

  11. 11

    Nakashiba T, Young JZ, McHugh TJ, Buhl DL, and Tonegawa S: "Inducible, Reversible Inhibition of Synaptic Transmission Reveals the Role of CA3 Output in Hippocampal Learning and Memory.", Science, 319(5876), 1260-4 (2008)

  12. 12

    McHugh TJ, Jones MW, Quinn JJ, Balthasar N, Coppari R, Elmquist JK, Lowell BB, Fanselow MS, Wilson MA, and Tonegawa S: "Dentate gyrus NMDA receptors mediate rapid pattern separation in the hippocampal network.", Science, 317(5834), 1994-9 (2007)

  13. 13

    McHugh TJ, Blum KI, Tsien JZ, Tonegawa S, and Wilson MA.: "Impaired hippocampal representation of space in CA1-specific NMDAR1 knockout mice.", Cell, 87(7), 1339-49 (1996)

プレスリリース 全て表示する